Ultrasound for targeted chemotherapy
Ultrasound for targeted chemotherapy
- Ultrasound to disgregate the gel sends the doses of the drug
Image: Harvard researchers have shown how ultrasound can temporarily alter an alginate hydrogel, which is held together by calcium ions (black dots) attached to acid chains (yellow). The gel self-repairs when the ultrasound stops (Photo courtesy of the Wyss Institute and the Harvard SEAS).
Ultrasound Ultrasound has begun to disintegrate the gel sends the doses of the drug used for chemotherapies (MedImaging, 2014; SEAS Harvard, 2014). The ultrasound must be applied continuously, or if the gel does not restructure again, this new technique was developed Under the direction of David J. Mooney, PhD, member principal of the board of the Wyss Institute for Engineering Inspired by Biology at Harvard University and a professor of bioengineering at the School of Engineering and Applied Sciences at Harvard.
"Our method contradicts the whole concept of sustained drug release and has a double effect," said Professor Mooney. "We have shown that we can use the hydrogels repeatedly and turn on and off the pulses of the drug at will and that the administration of the drugs by bursts when there is a low basal level seems to be particularly effective in destroying the cancer cells."
This new method not only serves for chemotherapy, it can potentially be applied in any disease that requires a localized drug.
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References:
MedImaging. (2014). Ultrasonido e hidrogeles permiten administrar la quimioterapia dirigida. Recuperado de https://www.medimaging.es/ultrasonido/articles/294753888/ultrasonido-e-hidrogeles-permiten-administrar-la-quimioterapia-dirigida.html
SEAS Harvard. (2014). Delivering drugs on cue. Recuperado de http://www.seas.harvard.edu/news/2014/06/delivering-drugs-cue
How to cite this article:
Nocetti, F.A. (2014). "Ultrasound for targeted chemotherapy". In NabbuBlog. Retrieved from http://nabbublog.blogspot.com/2014/10/ultrasound-for-targeted-chemotherapy.html